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j m'd fi'. "-,v'! .mr,'-,7-rr ,:~ Miss C. Elan .... m~ lw ° ° ..... ,-r~ SRE/PSB/46D-2 (Battelle) D,'~T£ S.R., Evelyn 3rd June, 1977 TABLES EX RD.14SI RESTRICTED Please prepare, for transmission tolBattelle, masters of the following ratifies from the above report. Page numbers should be deleted. Page 15 AE~Dendix 1''/ / Page 16 Appendix 2, including tenet Pages 51-62 Tables 33 to 44/ Pages 70-73 Tables 52 to 73 Please include the equations under tables 36, 37, 55 and 56 but do not include the text associated with the other tables. If possible, it would be helpful if the table numbers could be preceded by an "A" to become Tables A33-A44 and A52-A72. S oRo EV~YN ~D BAT Co LTD - MINNESOTA TOBACCO LITIGATION

[ I i I I ~RT TITLE: i J..'.l,:;..," u ,ll.,~J.I'~:. .. ~. ..u .... ; , ..... :'. t PROJECT JOB NO. : :,l ~, 5. " ~ FILE NO. : i" i.. b.. ,). AUTROR: ' J ": ~O~LKa.D~: ISSUE~: ~ u ,. DISTRIBUTION: SJC (~) : !~-"_: (~_) ." .'_tZ ~2> ~ ,~.,~ (l) . ..... '~) "" - 2_S .'i) -,'~ ~i) : C-TP a_. =_ (!) " DGF'~. : Library (2) TAPE P EF:1%q Check Li8% BindAn~: Z~/Qra~ No. : Photo#raphl No. : Re@uctlons: Total Pa~s: -)~" I "2,) C-"; : ~ (L.) Draft for typing (1) (4) (5) Prepa2e mlM~ter: Co=rect£on~ (i)' (2) wpare 1 Bound Co~J l~ue : Typing Cheoking D~te l~te Sent Reed / D~te Returned mu~J Author f/ S. B. z~ .-4-', v , ~.~ ic Z~te 7.z.77 '3~,,q7 Ii~.%er X~to This pro forma is intended to facilitate and detail the pro~m'eaI of @.R. A D.C. Repor~8 from the typescript 8ta@~ until ~hezepoz~ Am finally &ppx~ved and imR@d. ~ho~'~ f~T~ • hould ~e commenced a~ the time of the in/tial ~in~a~d ac=~E~ ~he 'ty'poIc:L'ipt (~ master ~er preparation) at all ~ubsequent eta4~e. It mASt be sen% to cemtz~.l filAngvith the master when the report Is iSmAed. Not.._ee: I. ~herever po88ible, dz~ft8 ~or %-yping ~hould bo wzltton in ink. ~. After i-/pin~, the ~I~ipt 8h,mala normally be re~ %0 the Au%~c~, 'who will eubIe~uently obtain~he Group Leader'I and Zs~ue~oe appx~wal. Circulation ~hould be determined by the Ie~aer. 4. The typescript mu~t not be premerlt~ for printing ~A%til ~e limaor ham AxtAtl~%le~ %he p~ fcrm~ a@aAn~% "Prepare Ma~ter". 5. After printing, one bound copy mast be returned to %he eerier for fiz~l &l~,~&l and ~he Issuer will ensure that one copy iI ~een by ~he M&na~r. BAT Co LTD - MINNESOTA TOBACCO LITIGATION O (.j-n -..-..4 o

INDEX HAS INDICATED GAP IN BATES RANGE HERE

A STArXSTXCAL ,.~Ys~s oF THE Wc~E.C~ OF REPORT NO. RD. l&81 RESTRICTED 22.4.1977 AUTHOR: E.~. Wilkea ZSSUED BY: N.E. Willis ¥ROG. EEF. 11.0S.01 DISTRIBUTION : Dr. S.J. Green Dr. D.C. FalCon L~bc&ry Copy No. 1 " " 2, 3 " " 4, 5 COP~NO: BAT Co LTD - MINNESOTA TOBACCO LITIGATION i r,,o

INDEX HAS INDICATED GAP IN BATES RANGE HERE

ZBWII2~IA6~-2 Group Research & DeTelopment Centre, British-American Tobacco Co. Ltd., SOUTHAMPTON. 22rid April, 1977 I A SZATISZIC~a.~SIS OF T~ n~C~D~C~ OF I"L~OUR-BEARING ANINALS ZN JANUS F..XI~ER~ B9 CReport No. KD.2481 Restricted) SU~IARYI The major conclusions to be drawn from th~s analysis are:- 1. Ethanol extraction reduces the tumor£aeniclty of the control tobacco. 2. Return of the material extracted by the ethanol to the tobacco does not completely restore the tumorigenicity of the control bland. Canadian PCL v£th "Garlach" additives has a lover tumorisenic activity than the extracted tobacco. Gerlach sheet has a lower tumorigenic activi=y ~han the Canadian PCL containins "Gerlach" additives. Gezlacb sheet prepared from ethanol extracted tobacco has a very low activity, and the effects of ethanol extraction and the Getl&ch process seem to be additive. 3~ , S, NOTE A copy of this report with Sugary I and Appendix lII deleted has been passed to the Battelle ~t£tute. Frankfurt-anr-Nain. for incorporation i~ their report. BAT Co LTD - MINNESOTA TOBACCO LITIGATION w

INDEX HAS INDICATED GAP IN BATES RANGE HERE

Zm,;/L~/46D-'2 Croup Research & Development Centre, Brltlsh-America-- Tobacco Co. Ltd., SOUTKkMmT0~. 22nd &priZ, 1977 A mV.L SXS n c cz (B, mport lqc. 1~.1481 ~ecric:ed) SUMHAEY The major conclulons to be drawn fro: this analys£s ate:- I. The extracted tobacco has a lower tumorlgen£c activity ~ the control blend. 2. Return of the extracted material to zhe tobacco does not completely restore the cumor£ien£c activity. 3. Sheet ucar£al 'A' has a lower tumor£Sen£c act£v£Cy :ha- ax:ractad tobacco. Sheet macer~al 'B' has a l~r tumor£gen£c acc£v£ty rAum macar£al 'A'. 5. Sheet materLAl 'C' has a lower Cumo=£semic activity cha: matar&al 'B'. Gr~ BAT Co LTD - MINNESOTA TOBACCO LITIGATION

INDEX HAS INDICATED GAP IN BATES RANGE HERE