Tobacco Documents Online

HK0269023 57707 5 CARBON MONOXIDE INHALATION--TIME FOR CLEARAIICE FROM BLOOD IN REVERSIBLE C01~ JAMA 230(7): 1064; 1974 ASTRUP, P 0UESTIO~: "How LONG WOULD IT TAKE FOR CARBON MONOXIDE TO BE CLEARED FROM THE BLOODs AS DETERMINED BY THE USUAL METHODS, AFTER EXPOSURE TO ENOUGH CARBON MONOXIDE TO PRODUCE COMA, YET ALLOW FOR COMPLETE RECOVERY?" ANSWER: "THE ELIMINATION OF CARBON MONOXIDE FROM 1~E BLOOD DE- PENDS,,,ON THE ALVEOLAR VENTILATION [,],,,THE OXYGEN PRESSURE OF INSPIRED AIR [,J [AGE, AND SEX ],,,, - mIN AN 18-YEAR-OLD MAN WITH NORMAL ALVEOLAR VENTILATION WHO IS BREATHING ATMOSPHERIC AIR, IT MIGHT BE EXPECTED TO TAKE i0 TO 12 HOURS FOR THE CARBOXYHEMOGLOBIN LEVEL TO DROP FROM, SAYs 50~ TO" ABOUT 5~, LEVELS NECESSARY TO REACH COMA RANGE FROM 35~ TO 40~ UP TO 80~, NONSMOKERS HAVE LEVELS BELOW 2~ AND SMOKERS FROM 2% TO 20%." /AM/ U C0P HOSP, COPENHAGEN, DEI;.IARK QUESTION AND ANSWERs CARBON MONOXIDE TOXICITY, BLOOD CARBON MONOXIDE CLEARANCE, BLOOD CARBON MONOXIDE CONTENT/ CAR.BOXYHEMOGLOBINs TIME FACTORS, BLOOD CARBONMONOXIDE INCREASE SMOKING CAUSATION 1, TOBACCO SMOKING, ~0NSMOKERSn AGE FACTORS, SEX FACTORS, ALVEOLAR VENTILATION, CARBON MONOXIDE EXPOSURE DURATION, AIR OXYGEN// ENGLISH LANGUAGE, COPENHAGEN RESIDENCE, DENMARK RESIDENCE [~I~ 9Ll COHG O1015