Bliley Lorillard
Genetic and Environmental Bases of Tobacco-related Behavior
Abstract
Documents for file Spears' various arguments in favor of funding genetics project, noting "it could have significant...benefits relating to statistics; would contribute toward the establishment of filial groups as valuable genetic study entities; and enhance knowledge of general non-tobacco science". Indicates possibility for "full term of ten years".
Fields
- Type
- MEMORANDUM
- Author
- Stevens, Arthur Joseph (LOR Sr. VP '89-95 and TI Communications)Served on Lorillard Board of Directors 1985-92, was Senior Vice President from 1989 to 1995, served as General Counsel for Lorillard '93-95. Served on Tobacco Institute Communications Committee.
- Copied
- Judge, Curtis H. (RJR Bd of Direct. '67-69, VP Mrkting '68; CEO of Lorillard)Curtis H. Judge served on the RJR Board of Directors from 1967-1969, Vice President of Marketing in 1968, and on the Advertising Committee. (Source: RJR Who's Who NMLRP)Also, CTR director, President of Lorrillard during 1970s-1980s.
- Spears, Alexander White, III (LOR President & CEO)
Associated with CTR, used as an expert in the Mississippi case. - Spears, Alexander White, III (LOR President & CEO)
- Named Person
- Judge, Curtis H. (RJR Bd of Direct. '67-69, VP Mrkting '68; CEO of Lorillard)Curtis H. Judge served on the RJR Board of Directors from 1967-1969, Vice President of Marketing in 1968, and on the Advertising Committee. (Source: RJR Who's Who NMLRP)Also, CTR director, President of Lorrillard during 1970s-1980s.
- Spears, Alexander White, III (LOR President & CEO)
Associated with CTR, used as an expert in the Mississippi case.- Fisher
- Spears, Alexander White, III (LOR President & CEO)
- Keyword
- Genetic factors
- Environmental factors
- Constitutional hypothesis
- Environmental factors
- Thesaurus Term
- tobacco industry structure
- industry response
- Behavioral Effects (Effects)
- human subject
- data analysis
- epidemiology
- industry response
Document Images
MEMORA/~DUM TO TP~E FILE:
Genetic and Environmental Bases ~of
Tobacco-Related Behavior
On April 2nd, Mr. Judge and I discussed with
.Spears by telephone his memorandum~o Mr. =Judge;of March 27,
1975 regarding the proposal for the captioned Industry-sponsored
research project.
Dr. spears is of the view that although this project
is not a complete solution to all smoking and health questions,
it could have significant tangential or serendipitous benefits
relating to statistics; would contribute toward~the establishment
of filial groups as valuable genetic Study entities; and enhance
knowledge of general non,tobacco science.
Dr. Spears emphasizes that this project should realistic-
ally be viewed minimaily as a five-year feasibility study~ with
a decision as to continuation not before three or four years.
Alex also believes that a full term of ten years can be
anticipated, because the question of whether the Fisher hypothesis
is correct is probably not answerable in five years.
We also spoke at length concerning Dr. Spears' explan-
ation of certain Of the genetic aspects of the project. Genetic
self selection refers to the fact that this project, in part,
will require a search for heretofore unrecognized genes or
indicators-of~genes~ which are self selected by smoking -- i.e.,
are ~here gene~~ which themselves discriminate among smokers
and non-smokers? :Th~ s~arch wiliLbe format least two as yet
unrecognized genes: One~d0minant gene among smokers which is
behavior related: the other dominant g~n~
~ ~
_ ~ occurrlng among a
~f~w smokers making them disease, prone~ - '
~ ~ ~
For~a variety of reasons, Alex-is-of~the~view the ~:
project shou!d~be supported.
However, it should be recognized
that this is_ very high research risk.if the on!y~objective were
proof of the Fisher hypothesis.
AJS : RS
cc: Mr. Judge
Dr. Spears
Arthur J, Stevens
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