Tobacco Documents Online

C CC: A. J. Stevens Tobacco Institute Newsletter INFORMING THE INDUSTRY OF NEWSWORTHY DEVELOPMENTS 18751 Street, Northwest, WOshinglon, D.G.,20006 • 202/457-4800i Susan M. Sluntx;.Editbr; Number 339 August 23, 1983'. )I i I r R@search ".COFFEE AND ALCOHOL HAVE BEEN ABSOLVED" as links to pancreatic cancer, reported UPI of Ameri'can Hea1!thiFoundation epid'emiologic study reportedlin Cancer Research (8/83)1. Although €rnst L. Wynder and others found no associ'ation between consumption of either beverage and pancreatic cancer, they reported'weak association with smoking. They conclude their study withia reminder of the Surgeon General"s 1964 "discussilonion judgment for causation in epidemiology.° As epidemiiologists deal wiith weak associ- ations, they say, data tend to be "stretched beyond their elasti'city." "By analogy, it woulid seem that the same criteria can be used to establish a findinlg,of 'no associati'on.' Although not as exciting to the investigator and certainly not to the media, establishing that no association exists between 2 variables a~.ocon9ludes importance to scientific knowledge," Wy __ GALLAGHER F1EDICAL REPORT - 9/2/83 COFFEE ALCOHOL INTAKE LINKED T10~PaNCREATITIS. Mayo Clinic researchers find coffee (with or without caffeine), caffeine itself may stimulate pancreas to secrete increased amounts of trysin (protein-digesting enzyme). Increased stimulationimay lead to pan- creatitis (painful inflammation of pancreas). Alcohol (especially when taken with heavy and/or fat-containing meal) known contributor to acute pancreatitis. Chronic, excessive alcohol intake leads to chronic pancreatitis with recurrent, acute attacks. Reduce risk by avoiding heavy, fat-containing,meals taken With,alcohol and/or coffee.

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