Tobacco Documents Online

Rrae Suhca_3ttea on Project F'?74(Strci:-, sr3 2'^an), Dra. Catte] 1 L3 . n 3 • ~ F .rt £wxFcS:CL'. r C7•^~•~i to ^:.^.CCrt3~•TI t`:c ir:"~ratiCn,F3 Of tl{A' 'no•+v '- trin °•~ 1°e _:, r•.oj, i:xntil Fe'rtsry l, 1; %?, . ~ been s ' x 3tt d . , C. cn 7iy:,ch4 Pohst C. Ha iett An k-giicatian for cor Li 3 . nuo teh ~,- has rc,t, -, Dr. I'An.r;; C ~-eGi?1 altha.r , y '•i u.~z t`~.~ q-d w ,a 'r.ia co1le u~~, p.. tren~ w a*Mr beea r. ed as p, i Sr~1 Yrtvc si ir tcr. 7U3 ~t3:e cc--Xee c° ath:•xoscl.c.^otic cis^~e as deter"-ny:i at r•.;Lf c-ay, ~.'i L i1 aa Iy o~ ecci 3hn t v~.ctlr:a,l:a, for c~e3s•~ioa rah l:abits o: 3i: e, Fr-1 ei'~i311g cza,3 A1t,.-,•,,~;h tY.r an„itc^ A + t x . ~ J arould be Iie:1 in an efPOrt toy > i,. x., ~*i~ y,, c,~ 3,,'r~ t a ci~i~yar.t:;r`ro: c., c,_t: st;~tr,.1~n;; beer L:~~ o.~• futura n].aaIn. In rcrc:ri4z the ~ rt 3 t~ ~ G .3 Zw x.~2•~'7Ls•c_ia`.:Lr?~~7 'L~;~ ~Ckark ~`-C7"'•.~J:BC;i C: ~•y o!:e }~ ~- ~5 O" r. r- Ya t.a cerc__~ry s's:o x?:; ha ~?; in t3:r r.t,,.~,._ ir.. ;4d • s- aL^a •Ci- ~_. va..culjs: ~ ~ ~ . ~ o_ . ,.e.::3M: F~o_~1e. (3) „aetih:: tlr•~ ?esicn;, '•.n otl=er ~~ •ts of' ^{,~ (l) :ze r.cci72cy k~.th a~.icr ct::~:'osc3erotic lcsio_s cc : be Ci'e:tcct. (2)' 1:e re3iaW:.Lity ol i:;~cr Mtic*,I tcan tra o3t~~Aned on the life L~Mfi- ^ ~~ l,:cOc auc;ctiora insi.u3c-j: (4) 4' ~ "ee'x:::.. ot --- m ,ear'_ „~ i3 ,TC_i,3 ~re C^ iri L32'ii st7 tl`>^>e, mr.ny' :.C :1C3 of c..:_;••-Y`lsUc C?'t,.^. CC•1:'Ci Dc ol;'~._^.irn-i by ccc. :!t-aUt!;n 5 Fr• , e'.:1~ () at l:i n:i., of coaeiuJ.foas ci,ouIci L•:± po:,aib?e ir t} e da*.:a could be coliectca c.:ic-I the eurrel . to ,~ . :ere rry rav;.- bcen ot:,eru. T:.t c:Pcrer:ce on ~,r_ro 3c:c~i ~ t• leN~ {, ~. r, ~ t c~. 4 u., l_.•._r.. 0 1 ttc o• rire thin': .J ~~~) ~~ 1i ~.c.~.liS.i ~. ,•'J~ 1G:. PiF~. ~.,y I E!`1F.(a, 7 ~t :i: 2'A J~n1, C l.`.:3 L•. =. C~fI~~ ~. ~.:, Od :~'.:C j~ ~.LJ. ~iC i'~~3~~ . IC..~• ~ J ' 3 _i _':~ J. C14.e ..-.. ~ i .. of , . .O_ 1i11Z:.; £ )J`r 3y ;:•1 t su*'•c tY:oc r•lvice r~s ,~i ;1 1 , ! i :a z 1 . >_ta ~ ; , *c c_ rsa t on taia ' ' L t~.: 2 tL'3'' CUJjC,.i: h•C^ CjC3~~~ C-3 ~. ~ k_. C=n c'o e:;'a^,1 r 4;? 1_. ,ctt ` ~ v r , c cnk. a.: al....• •~l c. , .~ ioa a-1 ~ Prc4'eat. M-)t, of the of t::3 L'x.LC_'L'~:_~L` 1.1Cik`~`LCLen.x:'C!] C,^J.?JS a t:a re, rati ;•, ia ts,,at L{a n L%.aa for £L ~i 't i i:: t~i:'? C 1•,. r e `_

`, he rccomizes diet.~ry in..'ormtioa a3 equalJ.y or c::xe Lrz*rt..nt, he sees this as r,•zch r.ore d.ifficult ar_d does not ittclv.de it in hi:a l.+r^.e.ent plan, thou3ir the r^.attAr 13 u_Ider cor.tinuirz study by hin colle:zs-ueo at tne University of Louisianx. "dith respect to other parts of the vacct+lar s;;atc.ey he hva a coroTar,r arteries. r.ot included in his proposaS to us, r;nica is corair._d; to study of the ': hopwa to develop a co11,ateral study of t'ais sys tem. Rhis, 7;:rever, is coJ.le^Z:e v:o is int.:: estrd prticulnrly in the cereb-resl circvJ aion cn3 The ccn£creaco d3d not reveal e-no#hrr studies nou urzv.emmy with use of tecrniques stu'ficiently siniJ.a.r to s-a;;,3est that any* poolin;; of data would be poa3ible. The subeo-ittee xsat, therefore, reach nju?~o:•.ent as to tt eooprrative Froject or by other rradificc.tiorr. investm^nt or whctiier it c.rabe rade a gocd ir,vests.ent by ektan ,ion into vhether the exger4it'ure rcqueatccl for the stated purpose3 fri11 be a roc1 With renueet to t'.le kin33 of corclu,ioia tYxzt be drr-^r tra-n thL~ vcr?: if it cnsr be ca.*ried cut uucccsoiWlly, th;.-r e seem to be three po:, :ibi].ities: (1) There ray be a m~it,i_re co_-relation between t•a••± de-zzce of ecror-q:y CrLcm o3elerosis a: J. t..e e=.~"t of c.. :.:in;. 2) .ncl e ray be a co •relatzvn, or ~3) incre rra.y be r~ cozr it:tion. If.there s1hauld be a pasitive correlation, tre Een:xrl chseo of getv'ir., some real perspective. other life habits co:L1d be st:.35o1 E:Lmul'tanrousJ.y °,,.?:ere wo-ald 'cc a bett^r corcltiwioa uas 3ti..c'ci.ficd or not, OS' ccrc.tie, if a suffici.nt mr-'aer of as e`other evidence that tobccc:o use is to he<zlt'sr, urethrs• this indict tobe.cco F:ou13' urcloubtrl7:y seize urm any such rt.:ult rnd e~,gloy it up the lvo~ess, or v'r.ether the asso,;iation rras inaree'~ oth_r interv --~dinte factors aal r.ot actually cc.uaa1. .~osz tir3?o are ea ;e•r to laca+r uhcif.r^ the smoisirl; Sa usA3 t1:e Ereater d<jToc of ciseTsz by s=;eZ-diri; sitLUtien v~s? 3 be rach as it i3 =a.lreac:.y. lf:..`t i:r, tie tro;Iid r;.t re•:11}• If t.':c-re should be a negutive correlation, tho d_;Tee of this would be one pu:;sibLe kT~otacsis. co <C1U=1:r, tyYt to'i•deco u3e .^a>_o.a*".a CiOF71 ti.:e i:i::?:^YO3eZG'i*UtiC D:^C~--L:3 iat:?VUJI conclu;i•rersss would be si:-~~i?ar. t;e wo1:].d not re<:J.ly be Ju,;tifi::d in If ther.; s1_7-A1d be r.o cxrcis.tien, t? c rssults would be r. ara conclussive, sir_ce if t'r.e precision of t: e c'atn ti:erc: sufficient to ^_:_' : it cer t i.2 t7mt t::c•re wa s e: ea1 lncZ c: c i- ~] .ticn En:.i r_Dt __ df a neti:cdolo&ic:+1 ind~ter:L:acy, Sfe could tia;2 corcl2a^ t. :;, tol:.acco uti_ aetl s:Liy c:cea not acceierate uthe;.•oacleroJls oll t)'c: coro::.Z` C•2'i.Cricc. ~ Ii L7 2•7?GG7i12_ 13 co*_'i.^;;t, the st•l:.dy tpj:::n••3 a3 er.^ble in w:icli "'nea3s we win bu'u t ils •r.e co .:i; J:oa, fcr C' tJr-I ( of i.e., sclc l;?Yie^11v trou-,h <<c na ' ~ ht in t::_ rc.:,lrz,r,_» 1 r hc: ,l..nea cr:-1 e:~c:: at t:_e ~ ~k3~ o ciu lJ 8•o~ps"). Y ~ i Cn dmg~ ~ ~ `=

Is ti:er epny b"is for GuiisJinZ. u:~t will be found? In a so^.e;:h.:.t €ir.,_i.]-:sr study., Snain fm::d po correlation between s.~sr3n;; can the mou.nt of di'scaJc in the crn•sno-anf arterzes. Our E,°f fortt3 .^zlGil.~,, th L.:re Z]-i:^z v:t.'''L.'~-.~Y Dr. ZiGTizel lF.'Gr'.?- 2?':3f'i t`i:3.'y rE':;'a ~ i~~ TS"• ~l t~.~asi x • • ~ - • s~Ct~.~~ of 2.u:r'cv..w~n .1p The ci:ae~' n? ~•4.ci?r:~,..i.ve in is ~ ~.1,::.1. Qi our L'.:iat ].m?Jo.,'t!?.a i: r:a;'rs'i+i G'xm If we Ca53?:ti^3'4 t,::'L' C~ ::t`• ' y` OiI by ..v .:._ .I'ate of C.'`4?:':?:.t7zc10"i°oSi s by diZ'GC U or i i.::'ly a3c~ =,:mm S.TOU}.Ct' S:;= to be G~::le clottfr ; ti-me or r.c :>atcari t is cCnsidvre-J. to : c suc.i. To detcr:aine s:}°.ct2:, r c:-ia'.ir,3 does or de:;a not fect the even rrc os le-Y `~.."~ 1J'~V ~.'. ~..~.^a..,..• ~ ^ n`.-^` of " ~. .i~~...~J' y eC~ir ull.. .~3 '~, .e rLi~i t~c Cl'at:._v vA~.,.'''_g on concer,'c, and I do not know of any r: wcl::,~aisms that have been ciezcMxi ed or episoo-ua when the ur.derlfi.r. ; co. ~l:ti.nns ~.ra c;~n 1ucive. uz; s is a h;t_r.o~itTs;tica.l. The two Cb3-_~xra''ioSls can be reConc3Z.ei1 by flrst~}3.^..Z tl3;.t. FimLl:iin!; Ijui y dil:ec.ly or ind':.:: 'c3C'.f:ly., COIit:.'].:bLii,e to "'i.}:G ,;u..;''c^.C-1:i)itE:t]:OYl Of an 2.Cui;e di C2 i j.:;J a posil:j.lre cor'1`C'~...t7 oIA bn lou{3e:1 Et:.'G:-UTi;s and r~roca;.^C'.lc?.l 1]3:Ci::'ctioYl• erZ the re;c:^olo;.;ic=,1 condition fou.:d on m"torpsy. Sho k L-~~.i._ -•- .g,roup geTlcr?1i 4<°.'.Z at?1:G.CiCIG2'C33j.s of the c4's'os.~..wy ai't£.`rj Gci, the o:7a,'mR:tiol: tr mi.ght cuZ,-,ea•t that rrohui:ly no coz:Te3.-~,_oz would be found bel`rw:;. n s*.:a?tins i Ho:r2vc-~ if one s.ss~~:.as t:~.Mt v..^vi n~~ 13 'c.' Cir oI~,:Lc l'an1.fCtii:~ of ractori:>. They have done reL.i:i•reiy little .:rauo:,.ic or ;;s-tGroZ.,,;ical voeh,,. stu,i;,r found no correlation te-In'reen s4,o :ir ; and the ir.c~.der_ce of snZ_4r.s At our conf e-rencey ~'noL:.~.s Iauber repoL ted that the Frmi.n^,iL~xa s~.`a.L;'t.'uL`v,ge>3ic re-1w::n in h~.' a G== GifiG.:'e2'it 5;:;C~f;:>> 'li;GlL:-~,''u'~:1::g and ~h 1^ ei'feca,,' .. of ~2:~ n:is ~~ rJer - on 1`•~1'.&CCrE• ~.~:' ~. sece i;_ y.~'?a 1 ~''~:~.-~ ~~"- ~''~~~-2~~° r • ~:..'» °1.7 ' ~~". -`.n ` ` ._s c c19:eL~:,.•y r;.~5..T..~.., ~.ci clt~ci...;_, ~:c.__r...,c~.-~os,~; in are I2~;:1 G:I°~' ClCi:'~1;j L'Ti , i.. ~ „ i • ~ d f.!TU:.t si,»:17.G.. ..G~k .'' V -!~ dG~![,I".F'il to Bi12 5r i«.T"'~ro.~',C Ji.JbE=o t}Z:~'_£e inh:.:1:3tj o22 upon a basic cl'C•t3: ro- Fl03JE'VCT'~ in a 2'ECE::1v Co>liCiE:me kTiVl3 I. s'7': ir'ZL'iL u?`_E.'., he ei::res3e:~ the cpL:iaon that en'3~TM:zl e-:-c=i':cnts co~.].~ be ~=~~ ~ T. `~~ ?~ . i ~ c~e, ..:r:i~;~f~~. c The r•o bicm my be fF:_part~...nt erso_+.;,h to justZi'y toth r~.~n ad1iT.al fi 1,71iL ~.-'s• I 1)1.v-t2 to j'i'.3r :i.iJ' diccu.`5viani fL1I' u`,ilai' with :s'i,P.:,'C "c._sel s:m ('rG.'."`e on f,:^..•~, 'E..~'1iF:^ work. MAct-Ml42e We L::iAJt deter~~i,e how far we mnL to ~r-ib?e on McGi31's nplro;ach. Fi.L' eR. 9 F.C1;se::