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RESEARCH CONFERENCE UNITED KINGDOM 840000
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ADDENDUM
It iS suggested that we discuss, briefly, two points whilst we are together
at the Research Conference.
I,
Attached is a copy of a recent article in the I.C.P.S. Bulletin.
To counter this and similar publications, it is proposed that we
try to get published, e.g. as a note in "Nature", something a]ong
the lines of the enclosed memo by Chris Proctor.
2.
You will recall the review by ESan Massoy on Vitamin A. He drew
attention to the possible benefits from the industry being seen
to be taking part in a Vitamin A health education programme in the
less-developed areas of the world. ObvimJS questions are: should
we? and how? Possible steps include INFOTAB involvement, and/or
publication of a de-natured version of Elan Massey's review.
C.I. AYRES

SINCE th, o* o I In hieh b
the h~'ahh and shortens th~
lives of cigarette smokers
has h00 s des%re m' smoke
beyond ~.ii doubt, r~-
searche~ have Iurned Iheir
exacerbated by a :,reeky
Su~feres ~om c*hstruclive
lung dis.'ase (chronic brn.-
chiI~s and emphyscmc),
more frequently the eyes trueaflergytotohacco~moke
; anginaofeffortordisea~eof
conflrmedby:obse~,atlonof appeaTs to be rare, asthraatc$
.~The eg artcrcs find lhc~;
iner©ased blinking rate), often find their wheeze
exercise Ioieraace subs~antl-
aIiy reduced by exposure to
q~2he low ¢onccntradon$ of
Ioba¢co smoke.
Several st L, dles have shown
Ihat children from houscholdu
where parents s~nokc suffer
from rcspiralory in{eclions
more oft_-n (h~ a children from
non-smoking homes.
There have ~1~o been four
studies in wnich the health of
~on-smokJng wives of hus-
bands who smoke have been
followed up [or long p~riods.
-:Two give convicting r'.2,ult~
but in valve ~umbcrs t~o s~L[
to produc~ convtncin~ data;
of Ihe othe~ one in Japan
f~und their inciccnce of lung
cancer In be over dotlb[c ~hat
in wives OF non-smoking -"
husbands.
As only ]$ 9c: cent of"
./3panes~ wom~n smoke h
seems that more women are
killed by pas~iv¢ e~posure
than by smoking themselves!
in Ihe USA. ~holved a small
i~¢rease in lung cancer m
pa~;ive smoker wives which
d~d not, howeveG reach a
statistically i~gni~ieanl level.
Aparl from causing annoy-
ance~ irtilatlon and eye sym-
ptoms in a majoriIy Of non-
~mokcs, "current ¢vldcnce
points to an increased
incldcnc~ of respiratory
d~sense in very ynu.~ c]'ild-
rcn; an Jnc~'cascd ~sk of smaLL
airway diseas~ in aduhs, and
,*~ ~crcas~d r~SK of lung
cancer", re~ulc~ng from
prolonged exposure to
~]g~reHe smoke.
The Royal College of Phys-
icians conc[udc~ that "non.
smokers at work and play, in
Ira nspnr~ and in public places
shonld I h~v~ the ~hl t~-
~hoo~e not lo be so exposed'•.
'~ ": "- t: f "-
• :: ..... .... =: ..:

A~ ~NNESTIGATION OF THE ATMOSPHER~/'/N
LONDON UNDERGROUND TRAINS
It has teen decided by London Transport that in order 'to make the
Underground railway cleaner, more comfortable and more attractive to
passengers', smoking is to be banned on all Underground trains, This
prohibition commenced on July 9th, 1984 and is to have a trial period of
one year. We have used measurements of the concentrations of some tobacco
smoke components to assess the ambient air in Underground trains before
and after the ban. A summary of these values is prepared ~n Table 1.
(Detailed results are given in Appendix A and B).
Before the total ban on smoking was introduced, smoking compartments
contained on average five times the concentration of ~icotine and four
times the concentration of airborne particles as compared to non-smoking
carriages. However, the concentrations of nicotine (c. 30 #g/m3) and
particulates (c. 0.7 mg/m3) found in the smoking areas are similar to
those that are likely to be encountered in typical offices and public
houses, and are far below recommended industrial limits foc safe exposure
(500 pg/m3 for nicotine). Levels of carbon monoxide (c. 3 ppm) were found
to be very similar in smoking and non-smoking compartments and at a
concentration far below both that which would be experienced when sitting
in a car in traffic (c, 6-9 ppm) and the industrial safety limit (50 ppm
for 8 hour exposure).
A similar set of experiments was performed a month after the e~forcememt
of non-smoking. Nicotine concentrations were found to be lower, but a ~.~
comparison of the levels of particulates and carbon monoxide found in
non-smoking carriages before and after the ban shows no change,

-2-
To conclude, the concentrations of nicotine, airborne particulates and
carbon monoxide experienced in compartments where smoking was permitted
before the ban were all found to he far below recommended industrial
threshold limits. Prohibiting smoking from all carriages had the affect
of reducing the levels of nicotine a~d particulates in all parts of the
train to those that would have been encountered in non-smoking areas prior
to the ban. The carbon monoxide level was seen to be of a similar value
whether smoking was permitted or not. Concentrations of TPM and nicotine
found on platforms have not noticeably changed.
TABLE 1
Typical concentrations of tobacco smoke components encountered in the
London Underground,
Location Nicotine Airborne
Carbon
concentration Particulates
Monoxide
~g/m3 mg/m3
ppm
Smoking compartments
(before ban)
Non-smoking compartments
(before ban)
Non-smoking compartments
(after ban)
Platform
(both before and after)
Ratio of smoking/
~on-smoking compartments
before ban
Ratio of non-smoking
before ban/non-smoking
after ban
32
7
3
c.20
5
2
0.63
0.18
0,18
c.0.30
4
3.5
3
3
c.4
1
1
t,,,#

-3-
APPENDIX A
Concentrations of tobacco smoke components encountered in smoking and non-smoking
compartments of London Underground trains prior to prohibition of smoking.
Thursday 28th dune~ 1984
Time Type of
Compartment
13.00-13.55 NS
14.00-14.55 S
16.00-15.55 NS
17.00-18.00 S
Nicotine Concentration Airborne Particulates Carbon Monoxide
~g/m3 mg/m3 ppm
4 0.11 3
26 0.68 3
2 0.13 3
21 0.70 3
Wednesday 4th July~ 1984
Time
08.30-09.00
09.00-09.31
09.30-18,00
SO.O0-1O.30
i0.30-11,00
18,40-19.10
19.10-19.40
19.40-20.10
Type of *
Compartment
NS
NS
NS
NS
S "
Nicotine Concentration
~9/m3
32
12
74
2O
Airborne Particulates
mg/m3
0.19
0.87
0.20
0.88
0.18
0.31
0.24
Carbon Monoxide
ppm
36 0.33
* NS, no smoking, S, smoking

-4-
Q
APPENDIX B
Concentrations of tobacco smoke components encountered on platforms and in the
compartments of London Underground trains after the prohibition of smoking
in all carriages.
Wednesday ist August~ 1984
Time
Location
Nicotine Concentration
~g/m3
i0.25-i0,55 Embankment 26
platform
10.55-12.00 Circle Line I
:ompartment
12.30-13,30
Embankmen%!
platform
13.30-14.30
14.30-15.30
5.30-16.30
2
2
23
Airborne Particulates
mg/m3
0.30
0.19
0.17
Carbon Monoxide
ppm
4
3
0.20 3
0.25 3
0.36 4
Tuesday 7th August~ 1984
09.30-10.30
platform
10.30-11.30 3ircle Line
compartment
11.30-12.30I
12.30-13.30
14.00-15.00 Embankment
platform
15.00-16.001Circle Line
compartment
16.00-17.00
18
4
3
3
14
3
5 '
0.27 4
0.17 2
0.16
0.16
0.25
0.17
0.19
4
3
&l
3

(
CONTENTS
ATTENDEES IResearcb & Marketing)
AGENDA
©
r
k_)
j3,
J4.
5,
6,
7,
SUMMARIES OF RECENT TECHNICAL EXCHANGE MEETINGS:
- BIOLOGICAL (SOUTHAMPTON
- NICOTINE (SOUTHAMPTON)
- SMOKING 3EHAVIOU~IMARKETING ~MONTREALI
- FLAVOURIST (LOUISVILLE1
- STRUCTURED CREATI ITY (SDUTHAMPTO~)
- NEAR INFRA-RED (SOUTHAMPTON.
SUMMARIES OF GR~DC ACTIVITIES ON :
- SIDESTREAM
- PSYCHOLOGY ....
PROPOSED REVISIONS TO IROUP R&D PROGRAMME.
LISTING OF RECENT TECHNICAL EXCHANGE MEETINGS,
AND SUGGESTION~ FOR :UTURE MEETINGS : if .,.~
FORECASTED RESOURCE ALLOCATION
AN[ GR&[] BUDGET FOF 19D5
8
GR~DU ORGANI SATION
L

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( (
C
(
RESEARCH
~BSTRALIA
BRAZIL
CANADA
GERMANY
U.S.A.
U.K,
MARKETING
AUSTRALIA
BRAZIL
CANADA
GERMANY
U,S,A.
U.K,
aTTENDEES
MR. P.M. DENTON
MR. R.G. NICHOLLS
. DR, C.J.P, DE SlQUEIRA
DR, P.J. DUNN
DR, S.R. MASSEY .....
MR. E. RITTERSHAUS
DR, F, SEEHOFER
MR. E.E. KOHNHORST
DR. R,A. SANFORD
L.C,F, BLACKMAN
DR. C,I. AYRES
DR. R. BINNS
A.L, BEARD
M,J. HARD&ICN
MR. A. CHOWN
MR. W. ROSE
MR. F. ~NDRADB
MR. W. KNO~
MR. R. BE~ON
MR. W. BEINEMANN
MR, E. PARR~CK
MR. LM. ~'EATH ~
MR. J.A.B. KELLAGHER
MR. P.M. B]NGHA~ ~'~
MR. G.O. BROOKS
DR. T, BIRJI ~'~
GO
